Research Overview

The Soniat lab focuses on determining mechanisms of genome maintenance. In particular, we use a combination of structural biology, single-molecule biophysics, biochemistry, and cell biology techniques to decipher how molecular machines involved in DNA repair and telomere maintenance protect genomic integrity. Ultimately, our goal is to increase our understanding of how genome instability contributes to aging and cancer and to aid in the development of new strategies to delay age-related diseases.